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PON-SC – program for identifying steric clashes caused by amino acid substitutions
BACKGROUND: Amino acid substitutions due to DNA nucleotide replacements are frequently disease-causing because of affecting functionally important sites. If the substituting amino acid does not fit into the protein, it causes structural alterations that are often harmful. Clashes of amino acids caus...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707825/ https://www.ncbi.nlm.nih.gov/pubmed/29187139 http://dx.doi.org/10.1186/s12859-017-1947-7 |