Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling

The use of organic chemistry principles and prediction techniques has enabled the development of new bioorthogonal reactions. As this “toolbox” expands to include new reaction manifolds and orthogonal reaction pairings, the continued development of existing reactions remains an important objective....

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Detalles Bibliográficos
Autores principales: Lambert, William D., Scinto, Samuel L., Dmitrenko, Olga, Boyd, Samantha J., Magboo, Ronald, Mehl, Ryan A., Chin, Jason W., Fox, Joseph M., Wallace, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708333/
https://www.ncbi.nlm.nih.gov/pubmed/28752889
http://dx.doi.org/10.1039/c7ob01707c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708333/
https://www.ncbi.nlm.nih.gov/pubmed/28752889
http://dx.doi.org/10.1039/c7ob01707c

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