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Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium
Epoxide hydrolase (EH) enzymes catalyze the hydration of racemic epoxides to yield their corresponding vicinal diols. These enzymes present different enantio- and regioselectivity depending upon either the substrate structure or the substitution pattern of the epoxide ring. In this study, we computa...
Autores principales: | Serrano-Hervás, Eila, Garcia-Borràs, Marc, Osuna, Sílvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708342/ https://www.ncbi.nlm.nih.gov/pubmed/29026902 http://dx.doi.org/10.1039/c7ob01847a |
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