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Screening for precancerous anal lesions with P16/Ki67 immunostaining in HIV-infected MSM

BACKGROUND: Screening of anal cancer in HIV-infected MSM with anal cytology results in high rates of false positive results and elevated burden of high-resolution anoscopies. High-risk HPV up-regulates p16 and Ki67 expression in epithelial cells. We assessed the usefulness of P16/Ki-67 immunostainin...

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Detalles Bibliográficos
Autores principales:	Serrano-Villar, Sergio, Hernández-Novoa, Beatriz, de Benito, Amparo, del Romero, Jorge, Ocampo, Antonio, Blanco, José Ramón, Masiá, Mar, Sendagorta, Elena, Sanz, Gonzalo, Moreno, Santiago, Pérez-Molina, José A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708629/ https://www.ncbi.nlm.nih.gov/pubmed/29190817 http://dx.doi.org/10.1371/journal.pone.0188851

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