Cargando…

Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat

BACKGROUND: Reduced growth and osteopenia are common in individuals with cystic fibrosis (CF). Additionally, improved weight and height are associated with better lung function and overall health in the disease. Mechanisms for this reduction in growth are not understood. We utilized a new CFTR knock...

Descripción completa

Detalles Bibliográficos
Autores principales: Stalvey, Michael S., Havasi, Viktoria, Tuggle, Katherine L., Wang, Dezhi, Birket, Susan, Rowe, Steve M., Sorscher, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708703/
https://www.ncbi.nlm.nih.gov/pubmed/29190650
http://dx.doi.org/10.1371/journal.pone.0188497