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Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat
BACKGROUND: Reduced growth and osteopenia are common in individuals with cystic fibrosis (CF). Additionally, improved weight and height are associated with better lung function and overall health in the disease. Mechanisms for this reduction in growth are not understood. We utilized a new CFTR knock...
Autores principales: | Stalvey, Michael S., Havasi, Viktoria, Tuggle, Katherine L., Wang, Dezhi, Birket, Susan, Rowe, Steve M., Sorscher, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708703/ https://www.ncbi.nlm.nih.gov/pubmed/29190650 http://dx.doi.org/10.1371/journal.pone.0188497 |
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