Cargando…
Lupus nephritis progression in FcγRIIB(-/-)yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease
FcγRIIB(-/-)yaa mice develop severe lupus glomerulonephritis due to lack of an inhibitory immune cell receptor combined with a Y-chromosome linked autoimmune accelerator mutation. In the present study, we have investigated nephritis development and progression in FcγRIIB(-/-)yaa mice to find shared...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708736/ https://www.ncbi.nlm.nih.gov/pubmed/29190833 http://dx.doi.org/10.1371/journal.pone.0188863 |