Cargando…

ERRα protein is stabilized by LSD1 in a demethylation-independent manner

The LSD1 histone demethylase is highly expressed in breast tumors where it constitutes a factor of poor prognosis and promotes traits of cancer aggressiveness such as cell invasiveness. Recent work has shown that the Estrogen-Related Receptor α (ERRα) induces LSD1 to demethylate the Lys 9 of histone...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carnesecchi, Julie, Cerutti, Catherine, Vanacker, Jean-Marc, Forcet, Christelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708767/ https://www.ncbi.nlm.nih.gov/pubmed/29190800 http://dx.doi.org/10.1371/journal.pone.0188871

Ejemplares similares

LSD1-ERRα complex requires NRF1 to positively regulate transcription and cell invasion
por: Zhang, Ling, et al.
Publicado: (2018)

miR-135a Inhibits the Invasion of Cancer Cells via Suppression of ERRα
por: Tribollet, Violaine, et al.
Publicado: (2016)

Computational identification of new potential transcriptional partners of ERRα in breast cancer cells: specific partners for specific targets
por: Cerutti, Catherine, et al.
Publicado: (2022)

Repression of Osteoblast Maturation by ERRα Accounts for Bone Loss Induced by Estrogen Deficiency
por: Gallet, Marlène, et al.
Publicado: (2013)

The orphan receptor ERRα interferes with steroid signaling
por: Teyssier, Catherine, et al.
Publicado: (2008)

A Cell-Based Method to Detect Agonist and Antagonist Activities of Endocrine-Disrupting Chemicals on GPER
por: Périan, Séverine, et al.
Publicado: (2020)

Absence of ERRα in Female Mice Confers Resistance to Bone Loss Induced by Age or Estrogen-Deficiency
por: Teyssier, Catherine, et al.
Publicado: (2009)

LSD1: more than demethylation of histone lysine residues
por: Perillo, Bruno, et al.
Publicado: (2020)

Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation
por: Pan, Dongning, et al.
Publicado: (2013)

Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer
por: Gao, Shuai, et al.
Publicado: (2020)

A Live Cell Protein Complementation Assay for ORFeome-Wide Probing of Human HOX Interactomes
por: Jia, Yunlong, et al.
Publicado: (2023)

The Asymmetric Binding of PGC-1α to the ERRα and ERRγ Nuclear Receptor Homodimers Involves a Similar Recognition Mechanism
por: Takacs, Maria, et al.
Publicado: (2013)

Genome-Wide Studies of Histone Demethylation Catalysed by the Fission Yeast Homologues of Mammalian LSD1
por: Opel, Michael, et al.
Publicado: (2007)

Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells
por: Ghanbari, Faegheh, et al.
Publicado: (2020)

Inhibition of ERK signaling for treatment of ERRα positive TNBC
por: Musheyev, David, et al.
Publicado: (2023)

ERRα as a Bridge Between Transcription and Function: Role in Liver Metabolism and Disease
por: Xia, Hui, et al.
Publicado: (2019)

Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4
por: Vernier, Mathieu, et al.
Publicado: (2020)

ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer
por: Deblois, Geneviève, et al.
Publicado: (2016)

ERRα fosters running endurance by driving myofiber aerobic transformation and fuel efficiency
por: Xia, Hui, et al.
Publicado: (2023)

Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells
por: Deng, Chao-Yang, et al.
Publicado: (2022)

Association of Irisin/FNDC5 with ERRα and PGC-1α Expression in NSCLC
por: Nowińska, Katarzyna, et al.
Publicado: (2022)

Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication
por: Tu, Wen Juan, et al.
Publicado: (2021)

Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα
por: Yan, Ming, et al.
Publicado: (2016)

The Catalytic-Dependent and -Independent Roles of Lsd1 and Lsd2 Lysine Demethylases in Heterochromatin Formation in Schizosaccharomyces pombe
por: Marayati, Bahjat F., et al.
Publicado: (2020)

Multifaceted Transcriptional Network of Estrogen-Related Receptor Alpha in Health and Disease
por: Cerutti, Catherine, et al.
Publicado: (2023)

To Err Is Human, to Forgive Is Pharmacodynamic
por: Phillips, Patrick P. J., et al.
Publicado: (2022)

To Err Is Human, to Forgive Divine
por: Fincke, B.
Publicado: (1891)

Genomic Convergence among ERRα, PROX1, and BMAL1 in the Control of Metabolic Clock Outputs
por: Dufour, Catherine R., et al.
Publicado: (2011)

Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)
por: Sakane, Naoki, et al.
Publicado: (2011)

LSD1-mediated demethylation of OCT4 safeguards pluripotent stem cells by maintaining the transcription of PORE-motif-containing genes
por: Dan, Songsong, et al.
Publicado: (2021)

High Salt Diet Affects Renal Sodium Excretion and ERRα Expression
por: Wang, Dan, et al.
Publicado: (2016)

Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective
por: Suresh, S. N., et al.
Publicado: (2018)

Cholesterol as an Endogenous ERRα Agonist: A New Perspective to Cancer Treatment
por: Casaburi, Ivan, et al.
Publicado: (2018)

ERRα is an aggressive factor in lung adenocarcinoma indicating poor prognostic outcomes
por: Li, Ping, et al.
Publicado: (2019)

OR14-04 A Novel ERRα-Dependent Insulin Signaling Pathway
por: Xia, Hui, et al.
Publicado: (2020)

ERRα protects against sepsis-induced acute lung injury in rats
por: Xia, Wenfang, et al.
Publicado: (2023)

Estrogen related receptor α (ERRα) a promising target for the therapy of adrenocortical carcinoma (ACC)
por: Casaburi, Ivan, et al.
Publicado: (2015)

PERM1 regulates energy metabolism in the heart via ERRα/PGC−1α axis
por: Oka, Shin-ichi, et al.
Publicado: (2022)

LSD1 binds to HPV16 E7 and promotes the epithelial-mesenchymal transition in cervical cancer by demethylating histones at the Vimentin promoter
por: Liu, Yuan, et al.
Publicado: (2016)

Author Correction: Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication
por: Tu, Wen Juan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n503nmutm8vg548t8h4mbchg38