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Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula
The infection caused by Trichomonas vaginalis is the most common but overlooked non-viral sexually transmitted disease worldwide. Treatment relies on one class of drugs, the 5-nitroimidazoles, but resistance is widespread. New drugs are urgently needed. We reported the effect of crude and purified s...
Autores principales: | de Brum Vieira, Patrícia, Silva, Nícolas Luiz Feijó, Menezes, Camila Braz, da Silva, Márcia Vanusa, Silva, Denise Brentan, Lopes, Norberto Peporine, Macedo, Alexandre José, Bastida, Jaume, Tasca, Tiana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708768/ https://www.ncbi.nlm.nih.gov/pubmed/29190689 http://dx.doi.org/10.1371/journal.pone.0188531 |
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