Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi

Complement is an important part of innate immunity. The alternative pathway of complement is activated when the main opsonin, C3b coats non-protected surfaces leading to opsonisation, phagocytosis and cell lysis. The alternative pathway is tightly controlled to prevent autoactivation towards host ce...

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Detalles Bibliográficos
Autores principales: Kolodziejczyk, Robert, Mikula, Kornelia M., Kotila, Tommi, Postis, Vincent L. G., Jokiranta, T. Sakari, Goldman, Adrian, Meri, Taru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708776/
https://www.ncbi.nlm.nih.gov/pubmed/29190743
http://dx.doi.org/10.1371/journal.pone.0188127

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