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APOE allele frequencies in suspected non-amyloid pathophysiology (SNAP) and the prodromal stages of Alzheimer’s Disease

Biomarker definitions for preclinical Alzheimer’s disease (AD) have identified individuals with neurodegeneration (ND+) without β-amyloidosis (Aβ-) and labeled them with suspected non-AD pathophysiology (SNAP). We evaluated Apolipoprotein E (APOE) ε2 and ε4 allele frequencies across biomarker defini...

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Detalles Bibliográficos
Autores principales: Hohman, Timothy J., Dumitrescu, Logan, Oksol, Amy, Wagener, Madison, Gifford, Katherine A., Jefferson, Angela L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708777/
https://www.ncbi.nlm.nih.gov/pubmed/29190651
http://dx.doi.org/10.1371/journal.pone.0188501

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