Time-gated detection of protein-protein interactions with transcriptional readout

Transcriptional assays, such as yeast two-hybrid and TANGO, that convert transient protein-protein interactions (PPIs) into stable expression of transgenes are powerful tools for PPI discovery, screens, and analysis of cell populations. However, such assays often have high background and lose inform...

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Detalles Bibliográficos
Autores principales: Kim, Min Woo, Wang, Wenjing, Sanchez, Mateo I, Coukos, Robert, von Zastrow, Mark, Ting, Alice Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708895/
https://www.ncbi.nlm.nih.gov/pubmed/29189201
http://dx.doi.org/10.7554/eLife.30233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708895/
https://www.ncbi.nlm.nih.gov/pubmed/29189201
http://dx.doi.org/10.7554/eLife.30233

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