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Effect of MDR1 C1236T polymorphism on cyclosporine pharmacokinetics: A systematic review and meta-analysis

BACKGROUND: Cyclosporine (CsA) is one of the immunosuppressive drugs, whose pharmacokinetic characteristics vary greatly among individuals. The published data reveal conflicting effects of the polymorphism of MDR1 exon 12 SNP C1236T on the pharmacokinetics of cyclosporine. This study aims to conduct...

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Detalles Bibliográficos
Autores principales: Chen, Zhe, Zhang, Lingli, Yang, Chunsong, Jiang, Zhimei, Shen, Hongxin, Gui, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708953/
https://www.ncbi.nlm.nih.gov/pubmed/29381954
http://dx.doi.org/10.1097/MD.0000000000008700