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Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature

INTRODUCTION: Essential thrombocythemia/thrombocytosis (ET) is characterized by increased bleeding and thrombosis risk during the perioperative period. We report the case of a woman with ET and sigmoid colon cancer, in whom the postoperative course was complicated by anastomotic bleeding. A systemat...

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Autores principales: Zhu, Yi, Jiang, HongGang, Chen, ZhiHeng, Lu, BoHao, Wu, JiaMing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708998/
https://www.ncbi.nlm.nih.gov/pubmed/29381999
http://dx.doi.org/10.1097/MD.0000000000008856
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author Zhu, Yi
Jiang, HongGang
Chen, ZhiHeng
Lu, BoHao
Wu, JiaMing
author_facet Zhu, Yi
Jiang, HongGang
Chen, ZhiHeng
Lu, BoHao
Wu, JiaMing
author_sort Zhu, Yi
collection PubMed
description INTRODUCTION: Essential thrombocythemia/thrombocytosis (ET) is characterized by increased bleeding and thrombosis risk during the perioperative period. We report the case of a woman with ET and sigmoid colon cancer, in whom the postoperative course was complicated by anastomotic bleeding. A systematic review was conducted to seek guidance for the management of such patient in the perioperative period. METHODS: A systematic literature review was conducted using EMBASE, Medline, and PubMed databases to detect relevant English language articles. Published studies with full-text articles were included. Two authors independently searched and extracted the data. Any differences were resolved by consensus. Studies on abdominal surgery were manually retrieved. RESULTS: Four case reports (including our case report) that described abdominal surgery in patients with ET were included. All patients were females, with a mean age of 47 years. Laparoscopic surgery was performed in 2 patients, and open surgery was performed in the other 2 patients. Two patients had postoperative bleeding that occurred on the first postoperative day. There was one case of pseudohyperkalemia after surgery and one case of Budd-Chiari syndrome caused by hepatic vein thrombosis. No guidelines for patients with ET undergoing abdominal surgery were found. CONCLUSION: In conclusion, there are currently no definitive guidelines for the perioperative management of patients with ET. Furthermore, there are few reports of ET in patients with malignancy undergoing surgery. Further studies in this unique group of patients are required.
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spelling pubmed-57089982017-12-07 Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature Zhu, Yi Jiang, HongGang Chen, ZhiHeng Lu, BoHao Wu, JiaMing Medicine (Baltimore) 7100 INTRODUCTION: Essential thrombocythemia/thrombocytosis (ET) is characterized by increased bleeding and thrombosis risk during the perioperative period. We report the case of a woman with ET and sigmoid colon cancer, in whom the postoperative course was complicated by anastomotic bleeding. A systematic review was conducted to seek guidance for the management of such patient in the perioperative period. METHODS: A systematic literature review was conducted using EMBASE, Medline, and PubMed databases to detect relevant English language articles. Published studies with full-text articles were included. Two authors independently searched and extracted the data. Any differences were resolved by consensus. Studies on abdominal surgery were manually retrieved. RESULTS: Four case reports (including our case report) that described abdominal surgery in patients with ET were included. All patients were females, with a mean age of 47 years. Laparoscopic surgery was performed in 2 patients, and open surgery was performed in the other 2 patients. Two patients had postoperative bleeding that occurred on the first postoperative day. There was one case of pseudohyperkalemia after surgery and one case of Budd-Chiari syndrome caused by hepatic vein thrombosis. No guidelines for patients with ET undergoing abdominal surgery were found. CONCLUSION: In conclusion, there are currently no definitive guidelines for the perioperative management of patients with ET. Furthermore, there are few reports of ET in patients with malignancy undergoing surgery. Further studies in this unique group of patients are required. Wolters Kluwer Health 2017-11-27 /pmc/articles/PMC5708998/ /pubmed/29381999 http://dx.doi.org/10.1097/MD.0000000000008856 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 7100
Zhu, Yi
Jiang, HongGang
Chen, ZhiHeng
Lu, BoHao
Wu, JiaMing
Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature
title Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature
title_full Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature
title_fullStr Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature
title_full_unstemmed Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature
title_short Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature
title_sort abdominal surgery in patients with essential thrombocythemia: a case report and systematic review of literature
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708998/
https://www.ncbi.nlm.nih.gov/pubmed/29381999
http://dx.doi.org/10.1097/MD.0000000000008856
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