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Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes
Accumulating evidence implicates innate immune activation in the pathobiology of myelodysplastic syndromes. A key myeloid-related inflammatory protein, S100A9, serves as a Toll-like receptor ligand regulating tumor necrosis factor-α and interleukin-1β production. The role of myelodysplastic syndrome...
Autores principales: | Cluzeau, Thomas, McGraw, Kathy L., Irvine, Brittany, Masala, Erico, Ades, Lionel, Basiorka, Ashley A., Maciejewski, Jaroslaw, Auberger, Patrick, Wei, Sheng, Fenaux, Pierre, Santini, Valeria, List, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709100/ https://www.ncbi.nlm.nih.gov/pubmed/28983059 http://dx.doi.org/10.3324/haematol.2016.158857 |
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