RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance

Ovarian cancer is the most deadly gynecological cancer and unlike most other neoplasms, survival rates for ovarian cancer have not significantly improved in recent decades. We show that RAD6, an ubiquitin conjugating enzyme is significantly overexpressed in ovarian tumors and its expression increase...

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Detalles Bibliográficos
Autores principales: Somasagara, Ranganatha R., Spencer, Sebastian M., Tripathi, Kaushlendra, Clark, David W., Mani, Chinnadurai, da Silva, Luciana Madeira, Scalici, Jennifer, Kothayer, Hend, Westwell, Andrew D., Rocconi, Rodney P., Palle, Komaraiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709226/
https://www.ncbi.nlm.nih.gov/pubmed/28806395
http://dx.doi.org/10.1038/onc.2017.279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709226/
https://www.ncbi.nlm.nih.gov/pubmed/28806395
http://dx.doi.org/10.1038/onc.2017.279

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