Synthesis, anti-angiogenic and DNA cleavage studies of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives

A series of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)piperidine-4-carboxamide derivatives 10(a–f), 12(a–c) and 14(a–c) were synthesized and characterized by FTIR, (1)H-NMR, mass spectral and elemental analysis. The efficacy of these derivatives to inhibit in vivo angiogenesi...

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Detalles Bibliográficos
Autores principales: Kambappa, Vinaya, Chandrashekara, G. K., Rekha, N. D., Shivaramu, Prasanna D., Palle, Komaraiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709256/
https://www.ncbi.nlm.nih.gov/pubmed/29189954
http://dx.doi.org/10.1186/s13065-017-0354-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709256/
https://www.ncbi.nlm.nih.gov/pubmed/29189954
http://dx.doi.org/10.1186/s13065-017-0354-5

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