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Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish

This data article contains descriptive and experimental data on spinal cord regeneration in larval zebrafish and its dependence on Wnt/β-catenin signaling. Analyzing spread of intraspinally injected fluorescent dextran showed that anatomical continuity is rapidly restored after complete spinal cord...

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Detalles Bibliográficos
Autores principales: Wehner, Daniel, Becker, Thomas, Becker, Catherina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709348/
https://www.ncbi.nlm.nih.gov/pubmed/29204466
http://dx.doi.org/10.1016/j.dib.2017.10.068
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author Wehner, Daniel
Becker, Thomas
Becker, Catherina G.
author_facet Wehner, Daniel
Becker, Thomas
Becker, Catherina G.
author_sort Wehner, Daniel
collection PubMed
description This data article contains descriptive and experimental data on spinal cord regeneration in larval zebrafish and its dependence on Wnt/β-catenin signaling. Analyzing spread of intraspinally injected fluorescent dextran showed that anatomical continuity is rapidly restored after complete spinal cord transection. Pharmacological interference with Wnt/β-catenin signaling (IWR-1) impaired restoration of spinal continuity. For further details and experimental findings please refer to the research article by Wehner et al. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish (Wehner et al., 2017) [1].
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spelling pubmed-57093482017-12-04 Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish Wehner, Daniel Becker, Thomas Becker, Catherina G. Data Brief Neuroscience This data article contains descriptive and experimental data on spinal cord regeneration in larval zebrafish and its dependence on Wnt/β-catenin signaling. Analyzing spread of intraspinally injected fluorescent dextran showed that anatomical continuity is rapidly restored after complete spinal cord transection. Pharmacological interference with Wnt/β-catenin signaling (IWR-1) impaired restoration of spinal continuity. For further details and experimental findings please refer to the research article by Wehner et al. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish (Wehner et al., 2017) [1]. Elsevier 2017-11-04 /pmc/articles/PMC5709348/ /pubmed/29204466 http://dx.doi.org/10.1016/j.dib.2017.10.068 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Neuroscience
Wehner, Daniel
Becker, Thomas
Becker, Catherina G.
Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish
title Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish
title_full Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish
title_fullStr Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish
title_full_unstemmed Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish
title_short Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish
title_sort restoration of anatomical continuity after spinal cord transection depends on wnt/β-catenin signaling in larval zebrafish
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709348/
https://www.ncbi.nlm.nih.gov/pubmed/29204466
http://dx.doi.org/10.1016/j.dib.2017.10.068
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