A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold

A synthetic method for diversely substituted tetrahydropyrrolo[1,2-a]quinolines was developed via CuCl-catalyzed cascade transformation of internal aminoalkynes with alkynes under microwave- irradiation.

Detalles Bibliográficos
Autores principales: Ma, Can-Liang, Zhao, Jin-Hao, Yang, Yong, Zhang, Min-Kui, Shen, Chao, Sheng, Rong, Dong, Xiao-Wu, Hu, Yong-Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709353/
https://www.ncbi.nlm.nih.gov/pubmed/29192158
http://dx.doi.org/10.1038/s41598-017-16887-0
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author Ma, Can-Liang
Zhao, Jin-Hao
Yang, Yong
Zhang, Min-Kui
Shen, Chao
Sheng, Rong
Dong, Xiao-Wu
Hu, Yong-Zhou
author_facet Ma, Can-Liang
Zhao, Jin-Hao
Yang, Yong
Zhang, Min-Kui
Shen, Chao
Sheng, Rong
Dong, Xiao-Wu
Hu, Yong-Zhou
author_sort Ma, Can-Liang
collection PubMed
description A synthetic method for diversely substituted tetrahydropyrrolo[1,2-a]quinolines was developed via CuCl-catalyzed cascade transformation of internal aminoalkynes with alkynes under microwave- irradiation.
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spelling pubmed-57093532017-12-06 A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold Ma, Can-Liang Zhao, Jin-Hao Yang, Yong Zhang, Min-Kui Shen, Chao Sheng, Rong Dong, Xiao-Wu Hu, Yong-Zhou Sci Rep Article A synthetic method for diversely substituted tetrahydropyrrolo[1,2-a]quinolines was developed via CuCl-catalyzed cascade transformation of internal aminoalkynes with alkynes under microwave- irradiation. Nature Publishing Group UK 2017-11-30 /pmc/articles/PMC5709353/ /pubmed/29192158 http://dx.doi.org/10.1038/s41598-017-16887-0 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Ma, Can-Liang
Zhao, Jin-Hao
Yang, Yong
Zhang, Min-Kui
Shen, Chao
Sheng, Rong
Dong, Xiao-Wu
Hu, Yong-Zhou
A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold
title A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold
title_full A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold
title_fullStr A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold
title_full_unstemmed A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold
title_short A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold
title_sort copper-catalyzed tandem cyclization reaction of aminoalkynes with alkynes for the construction of tetrahydropyrrolo[1,2-a]quinolines scaffold
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709353/
https://www.ncbi.nlm.nih.gov/pubmed/29192158
http://dx.doi.org/10.1038/s41598-017-16887-0
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