Cargando…

CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models

Colorectal cancers (CRCs) can be divided into four gene expression-based biologically distinct consensus molecular subtypes (CMS). This classification provides a potential framework for stratified treatment, but to identify novel CMS-drug associations, translation of the subtypes to pre-clinical mod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eide, Peter W., Bruun, Jarle, Lothe, Ragnhild A., Sveen, Anita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709354/ https://www.ncbi.nlm.nih.gov/pubmed/29192179 http://dx.doi.org/10.1038/s41598-017-16747-x

Ejemplares similares

Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
por: Smeby, Jørgen, et al.
Publicado: (2019)

Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
por: Eide, Peter W., et al.
Publicado: (2021)

Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
por: Smeby, Jørgen, et al.
Publicado: (2020)

Long noncoding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell‐intrinsic properties
por: Eide, Peter W., et al.
Publicado: (2019)

Spatial analysis and CD25-expression identify regulatory T cells as predictors of a poor prognosis in colorectal cancer
por: Bergsland, Christian H., et al.
Publicado: (2022)

Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer
por: Bruun, Jarle, et al.
Publicado: (2018)

Multilevel genomics of colorectal cancers with microsatellite instability—clinical impact of JAK1 mutations and consensus molecular subtype 1
por: Sveen, Anita, et al.
Publicado: (2017)

The expressed mutational landscape of microsatellite stable colorectal cancers
por: Sveen, Anita, et al.
Publicado: (2021)

Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies
por: Berg, Kaja C. G., et al.
Publicado: (2017)

De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
por: Moosavi, Seyed H., et al.
Publicado: (2021)

Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series
por: Bruun, Jarle, et al.
Publicado: (2014)

Transcriptome instability as a molecular pan-cancer characteristic of carcinomas
por: Sveen, Anita, et al.
Publicado: (2014)

Improved prognostication of glioblastoma beyond molecular subtyping by transcriptional profiling of the tumor microenvironment
por: Jeanmougin, Marine, et al.
Publicado: (2020)

Tumour-infiltrating CD8(+) lymphocytes and colorectal cancer recurrence by tumour and nodal stage
por: Glaire, Mark A., et al.
Publicado: (2019)

The Consensus Molecular Subtypes of Colorectal Cancer
por: Guinney, Justin, et al.
Publicado: (2015)

Correction: Tumour-infiltrating CD8(+) lymphocytes and colorectal cancer recurrence by tumour and nodal stage
por: Glaire, Mark A., et al.
Publicado: (2019)

Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer
por: Eilertsen, Ina A., et al.
Publicado: (2018)

Prediction of relapse-free survival according to adjuvant chemotherapy and regulator of chromosome condensation 2 (RCC2) expression in colorectal cancer
por: Bergsland, Christian H, et al.
Publicado: (2020)

TIN: An R Package for Transcriptome Instability Analysis
por: Johannessen, Bjarne, et al.
Publicado: (2015)

E‐cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
por: Bruun, Jarle, et al.
Publicado: (2021)

Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
por: Sveen, Anita, et al.
Publicado: (2011)

Consensus molecular subtype classification of colorectal adenomas
por: Komor, Malgorzata A, et al.
Publicado: (2018)

Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer
por: Smeby, Jørgen, et al.
Publicado: (2019)

MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer
por: Cekaite, Lina, et al.
Publicado: (2015)

Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2
por: Lopes, Nair, et al.
Publicado: (2019)

Multiregional assessment of CIMP in primary colorectal cancers: Phenotype concordance but marker variability
por: Flatin, Bjørnar T.B., et al.
Publicado: (2020)

Investigation of colorectal cancer in accordance with consensus molecular subtype classification
por: Sawayama, Hiroshi, et al.
Publicado: (2020)

Novel RNA variants in colorectal cancers
por: Hoff, Andreas M., et al.
Publicado: (2015)

Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
por: Berg, Kaja C. G., et al.
Publicado: (2019)

Context matters—consensus molecular subtypes of colorectal cancer as biomarkers for clinical trials
por: Fontana, E, et al.
Publicado: (2019)

Consensus molecular subtypes of colorectal cancer in clinical practice: A translational approach
por: Valenzuela, Guillermo, et al.
Publicado: (2021)

Implications of Intratumor Heterogeneity on Consensus Molecular Subtype (CMS) in Colorectal Cancer
por: Chowdhury, Saikat, et al.
Publicado: (2021)

MmCMS: mouse models’ consensus molecular subtypes of colorectal cancer
por: Amirkhah, Raheleh, et al.
Publicado: (2023)

Phospholipase C Isozymes Are Deregulated in Colorectal Cancer – Insights Gained from Gene Set Enrichment Analysis of the Transcriptome
por: Danielsen, Stine A., et al.
Publicado: (2011)

Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases
por: Kryeziu, Kushtrim, et al.
Publicado: (2021)

Distinct gut microbiome patterns associate with consensus molecular subtypes of colorectal cancer
por: Purcell, Rachel V., et al.
Publicado: (2017)

Consensus Molecular Subtypes (CMS) in Metastatic Colorectal Cancer - Personalized Medicine Decision
por: Rebersek, Martina
Publicado: (2020)

YAP/TAZ Signalling in Colorectal Cancer: Lessons from Consensus Molecular Subtypes
por: Mouillet-Richard, Sophie, et al.
Publicado: (2020)

Genomic landscape and expression profile of consensus molecular subtype four of colorectal cancer
por: Lu, Yujie, et al.
Publicado: (2023)

Clinical Value of Consensus Molecular Subtypes in Colorectal Cancer: A Systematic Review and Meta-Analysis
por: ten Hoorn, Sanne, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bqcs6774mspun194kj31epne9j