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Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes
Cell membranes are crowded and complex environments. To investigate the effect of protein-lipid interactions on dynamic organization in mammalian cell membranes, we have performed coarse-grained molecular dynamics simulations containing >100 copies of an inwardly rectifying potassium (Kir) channe...
Autores principales: | Duncan, Anna L., Reddy, Tyler, Koldsø, Heidi, Hélie, Jean, Fowler, Philip W., Chavent, Matthieu, Sansom, Mark S. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709381/ https://www.ncbi.nlm.nih.gov/pubmed/29192147 http://dx.doi.org/10.1038/s41598-017-16865-6 |
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