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Hepatic Crtc2 controls whole body energy metabolism via a miR-34a-Fgf21 axis

Liver plays a crucial role in controlling energy homeostasis in mammals, although the exact mechanism by which it influences other peripheral tissues has yet to be addressed. Here we show that Creb regulates transcriptional co-activator (Crtc) 2 is a major regulator of whole-body energy metabolism....

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Detalles Bibliográficos
Autores principales: Han, Hye-Sook, Choi, Byeong Hun, Kim, Jun Seok, Kang, Geon, Koo, Seung-Hoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709393/
https://www.ncbi.nlm.nih.gov/pubmed/29192248
http://dx.doi.org/10.1038/s41467-017-01878-6