Cargando…

Multiplex single-cell visualization of nucleic acids and protein during HIV infection

Technical limitations in simultaneous microscopic visualization of RNA, DNA, and proteins of HIV have curtailed progress in this field. To address this need we develop a microscopy approach, multiplex immunofluorescent cell-based detection of DNA, RNA and Protein (MICDDRP), which is based on branche...

Descripción completa

Detalles Bibliográficos
Autores principales:	Puray-Chavez, Maritza, Tedbury, Philip R., Huber, Andrew D., Ukah, Obiaara B., Yapo, Vincent, Liu, Dandan, Ji, Juan, Wolf, Jennifer J., Engelman, Alan N., Sarafianos, Stefan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709414/ https://www.ncbi.nlm.nih.gov/pubmed/29192235 http://dx.doi.org/10.1038/s41467-017-01693-z

Ejemplares similares

Visualization of HIV-1 RNA Transcription from Integrated HIV-1 DNA in Reactivated Latently Infected Cells
por: Ukah, Obiaara B., et al.
Publicado: (2018)

Effects of Moloney Leukemia Virus 10 Protein on Hepatitis B Virus Infection and Viral Replication
por: Puray-Chavez, Maritza N., et al.
Publicado: (2019)

Visualization of Positive and Negative Sense Viral RNA for Probing the Mechanism of Direct-Acting Antivirals against Hepatitis C Virus
por: Liu, Dandan, et al.
Publicado: (2019)

Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication
por: Gruenke, Paige R, et al.
Publicado: (2022)

HIV-1 Resistance to Islatravir/Tenofovir Combination Therapy in Wild-Type or NRTI-Resistant Strains of Diverse HIV-1 Subtypes
por: Cilento, Maria E., et al.
Publicado: (2023)

Acute Cerebral Infarct and Saddle Pulmonary Embolism in a Post-COVID-19 Patient Treated With Thrombolytics
por: Sampson, Christopher, et al.
Publicado: (2023)

Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis
por: Elliott, Jennifer L, et al.
Publicado: (2020)

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
por: Francis, Ashwanth C., et al.
Publicado: (2020)

Publisher Correction: HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
por: Francis, Ashwanth C., et al.
Publicado: (2020)

Glycosylated diphyllin as a broad-spectrum antiviral agent against Zika virus
por: Martinez-Lopez, Alicia, et al.
Publicado: (2019)

The Heteroaryldihydropyrimidine Bay 38-7690 Induces Hepatitis B Virus Core Protein Aggregates Associated with Promyelocytic Leukemia Nuclear Bodies in Infected Cells
por: Huber, Andrew D., et al.
Publicado: (2018)

Mechanisms of Action of the Host-Targeting Agent Cyclosporin A and Direct-Acting Antiviral Agents against Hepatitis C Virus
por: Liu, Dandan, et al.
Publicado: (2023)

Rotten to the core: antivirals targeting the HIV-1 capsid core
por: McFadden, William M., et al.
Publicado: (2021)

Drug Interactions in Lenacapavir-Based Long-Acting Antiviral Combinations
por: Cilento, Maria E., et al.
Publicado: (2022)

A facile Q-RT-PCR assay for monitoring SARS-CoV-2 growth in cell culture
por: Mugisha, Christian Shema, et al.
Publicado: (2020)

Multiplexed Nucleic Acid Programmable Protein Arrays
por: Yu, Xiaobo, et al.
Publicado: (2017)

Fr134 SARS-COV-2 INDUCES EPITHYELIAL-NEURONAL CROSSTALK STIMULATING VASOACTIVE INTESTINAL PEPTIDE RELEASE AS A POTENTIAL MECHANISM OF COVID-19-ASSOCIATED DIARRHEA
por: He, Peijian, et al.
Publicado: (2021)

Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches
por: Senaweera, Sameera, et al.
Publicado: (2021)

Novel PF74-like small molecules targeting the HIV-1 capsid protein: Balance of potency and metabolic stability
por: Wang, Lei, et al.
Publicado: (2021)

Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules
por: Vernekar, Sanjeev Kumar V., et al.
Publicado: (2020)

Activation of HIV-1 proviruses increases downstream chromatin accessibility
por: Shah, Raven, et al.
Publicado: (2022)

Sa1273: ENTERIC NEURONAL VASOACTIVE INTESTINAL PEPTIDE MEDIATES SARS-COV-2 ASSOCIATED DIARRHEA
por: Balasubramaniam, Arun, et al.
Publicado: (2022)

CRISPR-induced DNA reorganization for multiplexed nucleic acid detection
por: Karlikow, Margot, et al.
Publicado: (2023)

Massively multiplexed nucleic acid detection with Cas13
por: Ackerman, Cheri M., et al.
Publicado: (2020)

Design, Synthesis and Characterization of HIV-1 CA-Targeting Small Molecules: Conformational Restriction of PF74
por: Sahani, Rajkumar Lalji, et al.
Publicado: (2021)

SARS-CoV-2 Induces Epithelial-Enteric Neuronal Crosstalk Stimulating VIP Release
por: Balasubramaniam, Arun, et al.
Publicado: (2023)

Long-Acting Anti-HIV Drugs Targeting HIV-1 Reverse Transcriptase and Integrase
por: Singh, Kamal, et al.
Publicado: (2019)

Mechanism of Nucleic Acid Unwinding by SARS-CoV Helicase
por: Adedeji, Adeyemi O., et al.
Publicado: (2012)

CRISPR‐Enhanced Hydrogel Microparticles for Multiplexed Detection of Nucleic Acids
por: Roh, Yoon Ho, et al.
Publicado: (2023)

Global Rescue of Defects in HIV-1 Envelope Glycoprotein Incorporation: Implications for Matrix Structure
por: Tedbury, Philip R., et al.
Publicado: (2013)

Targeting the HIV-1 and HBV Capsids, an EnCore
por: McFadden, William M., et al.
Publicado: (2023)

Multiplexed smFRET Nucleic Acid Sensing Using DNA Nanotweezers
por: Kaur, Anisa, et al.
Publicado: (2023)

Emerging Multiplex Nucleic Acid Diagnostic Tests for Combating COVID-19
por: Akarapipad, Patarajarin, et al.
Publicado: (2022)

HIV Capsid and Integration Targeting
por: Engelman, Alan N.
Publicado: (2021)

Nucleic acid visualization with UCSF Chimera
por: Couch, Gregory S., et al.
Publicado: (2006)

Multiplex detection of clinical pathogen nucleic acids via a three-way junction structure-based nucleic acid circuit
por: Yu, Chunxu, et al.
Publicado: (2023)

Multiplexed detection of bacterial nucleic acids using Cas13 in droplet microarrays
por: Thakku, Sri Gowtham, et al.
Publicado: (2022)

DNA origami book biosensor for multiplex detection of cancer-associated nucleic acids
por: Domljanovic, Ivana, et al.
Publicado: (2022)

1029. Torus Synestia Nucleic Acid Analysis Platform for Fast, High Multiplex Analysis of Nucleic Acids With Single-Nucleotide Discrimination Level
por: Rockwood, Tyler, et al.
Publicado: (2021)

Multimodal Functionalities of HIV-1 Integrase
por: Engelman, Alan N., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ivmjn5q59iu3dfairehh30k7m1