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Effect of Src Kinase inhibition on Cytochrome c, Smac/DIABLO and Apoptosis Inducing Factor (AIF) Following Cerebral Hypoxia-Ischemia in Newborn Piglets

We have previously shown that cerebral Hypoxia-ischemia (HI) results in activation of Src kinase in the newborn piglet brain. We investigated the regulatory mechanism by which the pre-apoptotic proteins translocate from mitochondria to the cytosol during HI through the Src kinase. Newborn piglets we...

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Detalles Bibliográficos
Autores principales: Kratimenos, Panagiotis, Koutroulis, Ioannis, Agarwal, Beamon, Theocharis, Stamatios, Delivoria-Papadopoulos, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709433/
https://www.ncbi.nlm.nih.gov/pubmed/29192254
http://dx.doi.org/10.1038/s41598-017-16983-1