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A robust cell culture system supporting the complete life cycle of hepatitis B virus
The discovery of sodium taurocholate cotransporting polypeptide (NTCP) as the hepatitis B virus (HBV) receptor enabled researchers to create hepatoma cell lines susceptible to HBV infection. Infection in current systems, however, is inefficient and virus fails to spread. Infection efficiency is enha...
Autores principales: | Michailidis, Eleftherios, Pabon, Jonathan, Xiang, Kuanhui, Park, Paul, Ramanan, Vyas, Hoffmann, Hans-Heinrich, Schneider, William M., Bhatia, Sangeeta N., de Jong, Ype P., Shlomai, Amir, Rice, Charles M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709435/ https://www.ncbi.nlm.nih.gov/pubmed/29192196 http://dx.doi.org/10.1038/s41598-017-16882-5 |
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