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Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients
The error-related negativity (ERN), an evoked-potential that arises in response to the commission of errors, is an important early indicator of self-regulatory capacities. In this study we investigated whether brief mindfulness training can reverse ERN deficits in chronically depressed patients. The...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709439/ https://www.ncbi.nlm.nih.gov/pubmed/28975567 http://dx.doi.org/10.3758/s13415-017-0540-x |
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author | Fissler, Maria Winnebeck, Emilia Schroeter, Titus A. Gummbersbach, Marie Huntenburg, Julia M. Gärtner, Matti Barnhofer, Thorsten |
author_facet | Fissler, Maria Winnebeck, Emilia Schroeter, Titus A. Gummbersbach, Marie Huntenburg, Julia M. Gärtner, Matti Barnhofer, Thorsten |
author_sort | Fissler, Maria |
collection | PubMed |
description | The error-related negativity (ERN), an evoked-potential that arises in response to the commission of errors, is an important early indicator of self-regulatory capacities. In this study we investigated whether brief mindfulness training can reverse ERN deficits in chronically depressed patients. The ERN was assessed in a sustained attention task. Chronically depressed patients (n = 59) showed significantly blunted expression of the ERN in frontocentral and frontal regions, relative to healthy controls (n = 18). Following two weeks of training, the patients (n = 24) in the mindfulness condition showed a significantly increased ERN magnitude in the frontal region, but there were no significant changes in patients who had received a resting control (n = 22). The findings suggest that brief training in mindfulness may help normalize aberrations in the ERN in chronically depressed patients, providing preliminary evidence for the responsiveness of this parameter to mental training. |
format | Online Article Text |
id | pubmed-5709439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-57094392017-12-06 Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients Fissler, Maria Winnebeck, Emilia Schroeter, Titus A. Gummbersbach, Marie Huntenburg, Julia M. Gärtner, Matti Barnhofer, Thorsten Cogn Affect Behav Neurosci Article The error-related negativity (ERN), an evoked-potential that arises in response to the commission of errors, is an important early indicator of self-regulatory capacities. In this study we investigated whether brief mindfulness training can reverse ERN deficits in chronically depressed patients. The ERN was assessed in a sustained attention task. Chronically depressed patients (n = 59) showed significantly blunted expression of the ERN in frontocentral and frontal regions, relative to healthy controls (n = 18). Following two weeks of training, the patients (n = 24) in the mindfulness condition showed a significantly increased ERN magnitude in the frontal region, but there were no significant changes in patients who had received a resting control (n = 22). The findings suggest that brief training in mindfulness may help normalize aberrations in the ERN in chronically depressed patients, providing preliminary evidence for the responsiveness of this parameter to mental training. Springer US 2017-10-03 2017 /pmc/articles/PMC5709439/ /pubmed/28975567 http://dx.doi.org/10.3758/s13415-017-0540-x Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Article Fissler, Maria Winnebeck, Emilia Schroeter, Titus A. Gummbersbach, Marie Huntenburg, Julia M. Gärtner, Matti Barnhofer, Thorsten Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients |
title | Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients |
title_full | Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients |
title_fullStr | Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients |
title_full_unstemmed | Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients |
title_short | Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients |
title_sort | brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709439/ https://www.ncbi.nlm.nih.gov/pubmed/28975567 http://dx.doi.org/10.3758/s13415-017-0540-x |
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