Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP

The X-chromosome linked inhibitor of apoptosis (XIAP) is a multidomain metalloprotein involved in caspase inhibition and in copper homeostasis. It contains three zinc-binding baculoviral IAP repeats (BIR) domains, which are responsible for caspase interaction. Recently, it has been suggested that th...

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Detalles Bibliográficos
Autores principales: Hou, Meng-Meng, Polykretis, Panagis, Luchinat, Enrico, Wang, Xiao, Chen, Shen-Na, Zuo, Hui-Hui, Yang, Yin, Chen, Jia-Liang, Ye, Yansheng, Li, Conggang, Banci, Lucia, Su, Xun-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709467/
https://www.ncbi.nlm.nih.gov/pubmed/29192194
http://dx.doi.org/10.1038/s41598-017-16723-5

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