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Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge

Many of the approximately 165 proteins encoded by the African swine fever virus (ASFV) genome do not have significant similarity to known proteins and have not been studied experimentally. One such protein is DP148R. We showed that the DP148R gene is transcribed at early times postinfection. Deletio...

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Detalles Bibliográficos
Autores principales:	Reis, Ana L., Goatley, Lynnette C., Jabbar, Tamara, Sanchez-Cordon, Pedro J., Netherton, Christopher L., Chapman, David A. G., Dixon, Linda K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709585/ https://www.ncbi.nlm.nih.gov/pubmed/28978700 http://dx.doi.org/10.1128/JVI.01428-17

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