Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure

The effect of non-vitamin K antagonist oral anticoagulants on left atrial appendage (LAA) thrombus has not been fully elucidated. There are a few reports showing resolution of LAA thrombus with apixaban. An 84-year-old woman was admitted to our hospital due to acute exacerbation of chronic heart fai...

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Autores principales: Okada, Takenori, Takaekou, Yuji, Idei, Naomi, Ohashi, Norihiko, Kaseda, Shunichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709633/
https://www.ncbi.nlm.nih.gov/pubmed/28943564
http://dx.doi.org/10.2169/internalmedicine.8893-17
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author Okada, Takenori
Takaekou, Yuji
Idei, Naomi
Ohashi, Norihiko
Kaseda, Shunichi
author_facet Okada, Takenori
Takaekou, Yuji
Idei, Naomi
Ohashi, Norihiko
Kaseda, Shunichi
author_sort Okada, Takenori
collection PubMed
description The effect of non-vitamin K antagonist oral anticoagulants on left atrial appendage (LAA) thrombus has not been fully elucidated. There are a few reports showing resolution of LAA thrombus with apixaban. An 84-year-old woman was admitted to our hospital due to acute exacerbation of chronic heart failure and marked tachycardia with atrial fibrillation. She had permanent atrial fibrillation and was treated with warfarin; however, transthoracic echocardiography revealed a non-mobile thrombus in the LAA. Therefore, we switched warfarin to apixaban at a dose of 5 mg/day. After two weeks on that therapy, the thrombus in the LAA was successfully resolved.
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spelling pubmed-57096332017-12-04 Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure Okada, Takenori Takaekou, Yuji Idei, Naomi Ohashi, Norihiko Kaseda, Shunichi Intern Med Case Report The effect of non-vitamin K antagonist oral anticoagulants on left atrial appendage (LAA) thrombus has not been fully elucidated. There are a few reports showing resolution of LAA thrombus with apixaban. An 84-year-old woman was admitted to our hospital due to acute exacerbation of chronic heart failure and marked tachycardia with atrial fibrillation. She had permanent atrial fibrillation and was treated with warfarin; however, transthoracic echocardiography revealed a non-mobile thrombus in the LAA. Therefore, we switched warfarin to apixaban at a dose of 5 mg/day. After two weeks on that therapy, the thrombus in the LAA was successfully resolved. The Japanese Society of Internal Medicine 2017-09-25 2017-11-01 /pmc/articles/PMC5709633/ /pubmed/28943564 http://dx.doi.org/10.2169/internalmedicine.8893-17 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Okada, Takenori
Takaekou, Yuji
Idei, Naomi
Ohashi, Norihiko
Kaseda, Shunichi
Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure
title Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure
title_full Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure
title_fullStr Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure
title_full_unstemmed Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure
title_short Resolution of Left Atrial Appendage Thrombus with Apixaban in a Patient with Heart Failure
title_sort resolution of left atrial appendage thrombus with apixaban in a patient with heart failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709633/
https://www.ncbi.nlm.nih.gov/pubmed/28943564
http://dx.doi.org/10.2169/internalmedicine.8893-17
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