Tamoxifen-induced Lung Injury

Cases of drug-induced lung injury caused by tamoxifen are rare. A 74-year-old man underwent surgery for the treatment of right breast cancer; tamoxifen was administered as an adjuvant therapy after surgery. The patient developed cough and dyspnea and chest computed tomography showed ground glass opa...

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Detalles Bibliográficos
Autores principales: Etori, Satoshi, Nakano, Ryoji, Kamada, Hideki, Hosokawa, Keisuke, Takeda, Shinichi, Fukuhara, Masanori, Kenmotsu, Yoshiyuki, Ishimine, Atsushi, Sato, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709636/
https://www.ncbi.nlm.nih.gov/pubmed/28943550
http://dx.doi.org/10.2169/internalmedicine.8649-16
Descripción
Sumario:Cases of drug-induced lung injury caused by tamoxifen are rare. A 74-year-old man underwent surgery for the treatment of right breast cancer; tamoxifen was administered as an adjuvant therapy after surgery. The patient developed cough and dyspnea and chest computed tomography showed ground glass opacification in the lower lobe of the right lung. He was diagnosed with tamoxifen-induced lung injury. The diagnosis was made based on the exclusion of other causes and recurrence with the re-administration of tamoxifen. Physicians should therefore be aware of the potential for the development of tamoxifen-induced lung injury.

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