Tamoxifen-induced Lung Injury

Cases of drug-induced lung injury caused by tamoxifen are rare. A 74-year-old man underwent surgery for the treatment of right breast cancer; tamoxifen was administered as an adjuvant therapy after surgery. The patient developed cough and dyspnea and chest computed tomography showed ground glass opa...

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Autores principales: Etori, Satoshi, Nakano, Ryoji, Kamada, Hideki, Hosokawa, Keisuke, Takeda, Shinichi, Fukuhara, Masanori, Kenmotsu, Yoshiyuki, Ishimine, Atsushi, Sato, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709636/
https://www.ncbi.nlm.nih.gov/pubmed/28943550
http://dx.doi.org/10.2169/internalmedicine.8649-16
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author Etori, Satoshi
Nakano, Ryoji
Kamada, Hideki
Hosokawa, Keisuke
Takeda, Shinichi
Fukuhara, Masanori
Kenmotsu, Yoshiyuki
Ishimine, Atsushi
Sato, Kumiko
author_facet Etori, Satoshi
Nakano, Ryoji
Kamada, Hideki
Hosokawa, Keisuke
Takeda, Shinichi
Fukuhara, Masanori
Kenmotsu, Yoshiyuki
Ishimine, Atsushi
Sato, Kumiko
author_sort Etori, Satoshi
collection PubMed
description Cases of drug-induced lung injury caused by tamoxifen are rare. A 74-year-old man underwent surgery for the treatment of right breast cancer; tamoxifen was administered as an adjuvant therapy after surgery. The patient developed cough and dyspnea and chest computed tomography showed ground glass opacification in the lower lobe of the right lung. He was diagnosed with tamoxifen-induced lung injury. The diagnosis was made based on the exclusion of other causes and recurrence with the re-administration of tamoxifen. Physicians should therefore be aware of the potential for the development of tamoxifen-induced lung injury.
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spelling pubmed-57096362017-12-04 Tamoxifen-induced Lung Injury Etori, Satoshi Nakano, Ryoji Kamada, Hideki Hosokawa, Keisuke Takeda, Shinichi Fukuhara, Masanori Kenmotsu, Yoshiyuki Ishimine, Atsushi Sato, Kumiko Intern Med Case Report Cases of drug-induced lung injury caused by tamoxifen are rare. A 74-year-old man underwent surgery for the treatment of right breast cancer; tamoxifen was administered as an adjuvant therapy after surgery. The patient developed cough and dyspnea and chest computed tomography showed ground glass opacification in the lower lobe of the right lung. He was diagnosed with tamoxifen-induced lung injury. The diagnosis was made based on the exclusion of other causes and recurrence with the re-administration of tamoxifen. Physicians should therefore be aware of the potential for the development of tamoxifen-induced lung injury. The Japanese Society of Internal Medicine 2017-09-25 2017-11-01 /pmc/articles/PMC5709636/ /pubmed/28943550 http://dx.doi.org/10.2169/internalmedicine.8649-16 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Etori, Satoshi
Nakano, Ryoji
Kamada, Hideki
Hosokawa, Keisuke
Takeda, Shinichi
Fukuhara, Masanori
Kenmotsu, Yoshiyuki
Ishimine, Atsushi
Sato, Kumiko
Tamoxifen-induced Lung Injury
title Tamoxifen-induced Lung Injury
title_full Tamoxifen-induced Lung Injury
title_fullStr Tamoxifen-induced Lung Injury
title_full_unstemmed Tamoxifen-induced Lung Injury
title_short Tamoxifen-induced Lung Injury
title_sort tamoxifen-induced lung injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709636/
https://www.ncbi.nlm.nih.gov/pubmed/28943550
http://dx.doi.org/10.2169/internalmedicine.8649-16
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AT fukuharamasanori tamoxifeninducedlunginjury
AT kenmotsuyoshiyuki tamoxifeninducedlunginjury
AT ishimineatsushi tamoxifeninducedlunginjury
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