Cargando…
Akt inhibition improves long‐term tumour control following radiotherapy by altering the microenvironment
Radiotherapy is an important anti‐cancer treatment, but tumour recurrence remains a significant clinical problem. In an effort to improve outcomes further, targeted anti‐cancer drugs are being tested in combination with radiotherapy. Here, we have studied the effects of Akt inhibition with AZD5363....
Autores principales: | Searle, Emma J, Telfer, Brian A, Mukherjee, Debayan, Forster, Duncan M, Davies, Barry R, Williams, Kaye J, Stratford, Ian J, Illidge, Tim M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709765/ https://www.ncbi.nlm.nih.gov/pubmed/29084756 http://dx.doi.org/10.15252/emmm.201707767 |
Ejemplares similares
-
Reprogramming the tumour microenvironment by radiotherapy: implications for radiotherapy and immunotherapy combinations
por: Colton, Madyson, et al.
Publicado: (2020) -
Understanding the Effects of Radiotherapy on the Tumour Immune Microenvironment to Identify Potential Prognostic and Predictive Biomarkers of Radiotherapy Response
por: Cheng, Shuhui, et al.
Publicado: (2020) -
Hypoxia and oxidative stress in breast cancer: Tumour hypoxia – therapeutic considerations
por: Williams, Kaye J, et al.
Publicado: (2001) -
The effect of hypoxia on PD-L1 expression in bladder cancer
por: Smith, Vicky, et al.
Publicado: (2021) -
ZD1839 (‘Iressa’), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model
por: Williams, K J, et al.
Publicado: (2002)