SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis

Fibrosis and organ failure is a common endpoint for many chronic liver diseases. Much is known about the upstream inflammatory mechanisms provoking fibrosis and downstream potential for tissue remodeling. However, less is known about the transcriptional regulation in vivo governing fibrotic matrix d...

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Detalles Bibliográficos
Autores principales: Athwal, Varinder S, Pritchett, James, Llewellyn, Jessica, Martin, Katherine, Camacho, Elizabeth, Raza, Sayyid MA, Phythian‐Adams, Alexander, Birchall, Lindsay J, Mullan, Aoibheann F, Su, Kim, Pearmain, Laurence, Dolman, Grace, Zaitoun, Abed M, Friedman, Scott L, MacDonald, Andrew, Irving, William L, Guha, Indra N, Hanley, Neil A, Piper Hanley, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709769/
https://www.ncbi.nlm.nih.gov/pubmed/29109128
http://dx.doi.org/10.15252/emmm.201707860

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