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Weighted likelihood inference of genomic autozygosity patterns in dense genotype data
BACKGROUND: Genomic regions of autozygosity (ROA) arise when an individual is homozygous for haplotypes inherited identical-by-descent from ancestors shared by both parents. Over the past decade, they have gained importance for understanding evolutionary history and the genetic basis of complex dise...
Autores principales: | Blant, Alexandra, Kwong, Michelle, Szpiech, Zachary A., Pemberton, Trevor J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709839/ https://www.ncbi.nlm.nih.gov/pubmed/29191164 http://dx.doi.org/10.1186/s12864-017-4312-3 |
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