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A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India
BACKGROUND: Intellectual disability (ID) can be inherited in families through consanguineous marriage. The ID in an individual can be associated with the ID, epilepsy, and mental illness in their parents. Such connections can be seen more closely among consanguineous marriages in tribal and nontriba...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709876/ https://www.ncbi.nlm.nih.gov/pubmed/29204013 http://dx.doi.org/10.4103/jnrp.jnrp_104_17 |
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author | Lakhan, Ram Bipeta, Rajshekhar Yerramilli, Srinivasa S. R. R. Nahar, Vinayak K. |
author_facet | Lakhan, Ram Bipeta, Rajshekhar Yerramilli, Srinivasa S. R. R. Nahar, Vinayak K. |
author_sort | Lakhan, Ram |
collection | PubMed |
description | BACKGROUND: Intellectual disability (ID) can be inherited in families through consanguineous marriage. The ID in an individual can be associated with the ID, epilepsy, and mental illness in their parents. Such connections can be seen more closely among consanguineous marriages in tribal and nontribal population in India. OBJECTIVE: This study shows a few common patterns of the consanguineous relationship in the parents of children with ID in India. MATERIALS AND METHODS: This is a case series research design. Extreme or deviant case sampling was applied. Data were collected in homes, camps, and clinical settings in the Barwani district of Madhya Pradesh, India. The patterns of consanguineous marriages and the relationship between children with ID and their relatives with ID, epilepsy, and mental illness were analyzed and reported with pedigree charts. RESULTS: Multiple patterns of consanguineous marriages in tribal and nontribal populations were observed. ID was found to be associated in children with their relatives of the first, second, and third generations. CONCLUSION: ID may inherit in individuals from their relatives of the first, second, and third generations who have ID, epilepsy, or mental illness and married in the relationship. Appropriate knowledge, guidance, and counseling may be provided to potential couples before planning a consanguineous marriage. |
format | Online Article Text |
id | pubmed-5709876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-57098762017-12-04 A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India Lakhan, Ram Bipeta, Rajshekhar Yerramilli, Srinivasa S. R. R. Nahar, Vinayak K. J Neurosci Rural Pract Original Article BACKGROUND: Intellectual disability (ID) can be inherited in families through consanguineous marriage. The ID in an individual can be associated with the ID, epilepsy, and mental illness in their parents. Such connections can be seen more closely among consanguineous marriages in tribal and nontribal population in India. OBJECTIVE: This study shows a few common patterns of the consanguineous relationship in the parents of children with ID in India. MATERIALS AND METHODS: This is a case series research design. Extreme or deviant case sampling was applied. Data were collected in homes, camps, and clinical settings in the Barwani district of Madhya Pradesh, India. The patterns of consanguineous marriages and the relationship between children with ID and their relatives with ID, epilepsy, and mental illness were analyzed and reported with pedigree charts. RESULTS: Multiple patterns of consanguineous marriages in tribal and nontribal populations were observed. ID was found to be associated in children with their relatives of the first, second, and third generations. CONCLUSION: ID may inherit in individuals from their relatives of the first, second, and third generations who have ID, epilepsy, or mental illness and married in the relationship. Appropriate knowledge, guidance, and counseling may be provided to potential couples before planning a consanguineous marriage. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5709876/ /pubmed/29204013 http://dx.doi.org/10.4103/jnrp.jnrp_104_17 Text en Copyright: © 2017 Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Lakhan, Ram Bipeta, Rajshekhar Yerramilli, Srinivasa S. R. R. Nahar, Vinayak K. A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India |
title | A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India |
title_full | A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India |
title_fullStr | A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India |
title_full_unstemmed | A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India |
title_short | A Family Study of Consanguinity in Children with Intellectual Disabilities in Barwani, India |
title_sort | family study of consanguinity in children with intellectual disabilities in barwani, india |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709876/ https://www.ncbi.nlm.nih.gov/pubmed/29204013 http://dx.doi.org/10.4103/jnrp.jnrp_104_17 |
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