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MUNC18–1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development

While Munc18–1 interacts with Syntaxin1 and controls the formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) complex to regulate presynaptic vesicle fusion in developed neurons, this molecule is likely to be involved in brain development since its gene abnorma...

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Detalles Bibliográficos
Autores principales: Hamada, Nanako, Iwamoto, Ikuko, Tabata, Hidenori, Nagata, Koh-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709915/
https://www.ncbi.nlm.nih.gov/pubmed/29191246
http://dx.doi.org/10.1186/s40478-017-0498-5