The role of aberrant expression of T cell miRNAs affected by TNF-α in the immunopathogenesis of rheumatoid arthritis

BACKGROUND: Tumor necrosis factor-alpha (TNF-α) can cause diverse T cell dysfunctions in patients with rheumatoid arthritis (RA). It is involved in the regulation of microRNAs (miRNAs) expression in different cell types. We hypothesized that the expression of T cell miRNAs would be affected by TNF-α...

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Detalles Bibliográficos
Autores principales: Lai, Ning-Sheng, Yu, Hui-Chun, Tung, Chien-Hsueh, Huang, Kuang-Yung, Huang, Hsien-Bin, Lu, Ming-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709919/
https://www.ncbi.nlm.nih.gov/pubmed/29191214
http://dx.doi.org/10.1186/s13075-017-1465-z

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