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Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model

In neuroinflammatory disorders such as multiple sclerosis, the physiological function of the blood-brain barrier (BBB) is perturbed, particularly in demyelinating lesions and supposedly secondary to acute demyelinating pathology. Using the toxic non-inflammatory cuprizone model of demyelination, we...

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Detalles Bibliográficos
Autores principales:	Berghoff, Stefan A., Düking, Tim, Spieth, Lena, Winchenbach, Jan, Stumpf, Sina K., Gerndt, Nina, Kusch, Kathrin, Ruhwedel, Torben, Möbius, Wiebke, Saher, Gesine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710130/ https://www.ncbi.nlm.nih.gov/pubmed/29195512 http://dx.doi.org/10.1186/s40478-017-0497-6

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