Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?

For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the...

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Detalles Bibliográficos
Autores principales: Hurt, Aeron, Komadina, Naomi, Deng, Yi-Mo, Kaye, Matthew, Sullivan, Sheena, Subbarao, Kanta, Barr, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2017
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710658/
https://www.ncbi.nlm.nih.gov/pubmed/29183552
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.47.17-00731
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author Hurt, Aeron
Komadina, Naomi
Deng, Yi-Mo
Kaye, Matthew
Sullivan, Sheena
Subbarao, Kanta
Barr, Ian
author_facet Hurt, Aeron
Komadina, Naomi
Deng, Yi-Mo
Kaye, Matthew
Sullivan, Sheena
Subbarao, Kanta
Barr, Ian
author_sort Hurt, Aeron
collection PubMed
description For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis.
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spelling pubmed-57106582017-12-07 Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope? Hurt, Aeron Komadina, Naomi Deng, Yi-Mo Kaye, Matthew Sullivan, Sheena Subbarao, Kanta Barr, Ian Euro Surveill Rapid Communication For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis. European Centre for Disease Prevention and Control (ECDC) 2017-11-23 /pmc/articles/PMC5710658/ /pubmed/29183552 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.47.17-00731 Text en This article is copyright of The Authors, 2017. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Hurt, Aeron
Komadina, Naomi
Deng, Yi-Mo
Kaye, Matthew
Sullivan, Sheena
Subbarao, Kanta
Barr, Ian
Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
title Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
title_full Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
title_fullStr Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
title_full_unstemmed Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
title_short Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
title_sort detection of adamantane-sensitive influenza a(h3n2) viruses in australia, 2017: a cause for hope?
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710658/
https://www.ncbi.nlm.nih.gov/pubmed/29183552
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.47.17-00731
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