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Targeting protein geranylgeranylation slows tumor development in a murine model of prostate cancer metastasis

The isoprenoid biosynthetic pathway (IBP) plays a critical role in providing substrates and enzymes necessary for the post-translational modification and thus activation of a number of proteins involved in prostate cancer metastasis. Previous work by our lab found novel compound disodium [(6Z,11E,15...

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Detalles Bibliográficos
Autores principales:	Reilly, Jacqueline E., Neighbors, Jeffrey D., Hohl, Raymond J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710670/ https://www.ncbi.nlm.nih.gov/pubmed/27624889 http://dx.doi.org/10.1080/15384047.2016.1219817

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