Genetic deletion of Rnd3 in neural stem cells promotes proliferation via upregulation of Notch signaling

Rnd3, a Rho GTPase, is involved in the inhibition of actin cytoskeleton dynamics through the Rho kinase-dependent signaling pathway. We previously demonstrated that mice with genetic deletion of Rnd3 developed a markedly larger brain compared with wild-type mice. Here, we demonstrate that Rnd3 knock...

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Detalles Bibliográficos
Autores principales: Dong, Huimin, Lin, Xi, Li, Yuntao, Hu, Ronghua, Xu, Yang, Guo, Xiaojie, La, Qiong, Wang, Shun, Fang, Congcong, Guo, Junli, Li, Qi, Mao, Shanping, Liu, Baohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710772/
https://www.ncbi.nlm.nih.gov/pubmed/29207629
http://dx.doi.org/10.18632/oncotarget.20247

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