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Isoxazole compound ML327 blocks MYC expression and tumor formation in neuroblastoma

Neuroblastomas are the most common extracranial solid tumors in children and arise from the embryonic neural crest. MYCN-amplification is a feature of ∼30% of neuroblastoma tumors and portends a poor prognosis. Neural crest precursors undergo epithelial-to-mesenchymal transition (EMT) to gain migrat...

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Detalles Bibliográficos
Autores principales:	Rellinger, Eric J., Padmanabhan, Chandrasekhar, Qiao, Jingbo, Craig, Brian T., An, Hanbing, Zhu, Jing, Correa, Hernán, Waterson, Alex G., Lindsley, Craig W., Beauchamp, R. Daniel, Chung, Dai H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710904/ https://www.ncbi.nlm.nih.gov/pubmed/29207623 http://dx.doi.org/10.18632/oncotarget.19406

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