Sigma-1 and Sigma-2 receptor ligands induce apoptosis and autophagy but have opposite effect on cell proliferation in uveal melanoma

Uveal melanoma is the most common primary intraocular tumor in adults, with about 1200–1500 new cases occurring per year in the United States. Metastasis is a frequent occurrence in uveal melanoma, and outcomes are poor once distant spread occurs and no clinically significant chemotherapeutic protoc...

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Detalles Bibliográficos
Autores principales: Longhitano, Lucia, Castracani, Carlo Castruccio, Tibullo, Daniele, Avola, Roberto, Viola, Maria, Russo, Giuliano, Prezzavento, Orazio, Marrazzo, Agostino, Amata, Emanuele, Reibaldi, Michele, Longo, Antonio, Russo, Andrea, Parrinello, Nunziatina Laura, Volti, Giovanni Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710909/
https://www.ncbi.nlm.nih.gov/pubmed/29207628
http://dx.doi.org/10.18632/oncotarget.19556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710909/
https://www.ncbi.nlm.nih.gov/pubmed/29207628
http://dx.doi.org/10.18632/oncotarget.19556

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