Cargando…

Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma

Human osteosarcoma is considered a malignant tumor with poor prognosis that readily metastasizes. Tetrahydrocurcumin (THC) has been reported to have anti-tumor activity in numerous tumors. In addition, hypoxia-inducible factor-1α (HIF-1α) has been demonstrated to be associated with tumor metastasis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yan, Liu, Ying, Zou, Jilong, Yan, Lixin, Du, Wei, Zhang, Yafeng, Sun, Hanliang, Lu, Peng, Geng, Shuo, Gu, Rui, Zhang, Hongyue, Bi, Zhenggang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710911/ https://www.ncbi.nlm.nih.gov/pubmed/29207631 http://dx.doi.org/10.18632/oncotarget.19845

Ejemplares similares

Construction and analysis of a ceRNA-ceRNA network reveals two potential prognostic modules regulated by hsa-miR-335-5p in osteosarcoma
por: Chen, Yuxi, et al.
Publicado: (2018)

The Tumor Suppressor Role of miR-124 in Osteosarcoma
por: Geng, Shuo, et al.
Publicado: (2014)

miR-126 Functions as a Tumor Suppressor in Osteosarcoma by Targeting Sox2
por: Yang, Chenglin, et al.
Publicado: (2013)

Effects of siRNA-mediated HIF-1α gene silencing on angiogenesis in osteosarcoma
por: Zhang, Xu-dong, et al.
Publicado: (2017)

Retraction: The Tumor Suppressor Role of miR-124 in Osteosarcoma
por: Geng, Shuo, et al.
Publicado: (2019)

The Cancer Chemopreventive and Therapeutic Potential of Tetrahydrocurcumin
por: Lai, Ching-Shu, et al.
Publicado: (2020)

LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation
por: Zhang, Jingjing, et al.
Publicado: (2016)

Tetrahydrocurcumin Ameliorates Skin Inflammation by Modulating Autophagy in High-Fat Diet-Induced Obese Mice
por: Kim, Jung Eun, et al.
Publicado: (2021)

Curcumin Metabolite Tetrahydrocurcumin in the Treatment of Eye Diseases
por: Kao, Yu-Wen, et al.
Publicado: (2020)

Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model
por: Yoysungnoen, Bhornprom, et al.
Publicado: (2023)

MicroRNA‑224 promotes the sensitivity of osteosarcoma cells to cisplatin by targeting Rac1
por: Geng, Shuo, et al.
Publicado: (2016)

Wound healing: a new perspective on glucosylated tetrahydrocurcumin
por: Bhaskar Rao, Adari, et al.
Publicado: (2015)

Subchronic and Reproductive/Developmental Toxicity Studies of Tetrahydrocurcumin in Rats
por: Majeed, Muhammed, et al.
Publicado: (2019)

Positive Tetrahydrocurcumin-Associated Brain-Related Metabolomic Implications
por: Josifovska, Slavica, et al.
Publicado: (2023)

Increased levels of the long noncoding RNA, HOXA-AS3, promote proliferation of A549 cells
por: Zhang, Hongyue, et al.
Publicado: (2018)

CEACAM6 is associated with osteosarcoma metastasis and facilitates epithelial–mesenchymal transition in osteosarcoma cells
por: Wang, Zeyu, et al.
Publicado: (2018)

Retraction: Yang, C., et al. miR-126 Functions as a Tumor Suppressor in Osteosarcoma by Targeting Sox2. Int. J. Mol. Sci. 2014, 15, 423–437, doi:10.3390/ijms15010423
por: Yang, Chenglin, et al.
Publicado: (2018)

Explore the multitarget mechanism of tetrahydrocurcumin preventing on UV-induced photoaging mouse skin
por: Xu, Chuan, et al.
Publicado: (2022)

Non-covalent proteasome inhibitor PI-1840 induces apoptosis and autophagy in osteosarcoma cells
por: Chen, Yuxi, et al.
Publicado: (2019)

Regulation of the Epithelial to Mesenchymal Transition in Osteosarcoma
por: Hinton, Kristin, et al.
Publicado: (2023)

Tetrahydrocurcumin-Related Vascular Protection: An Overview of the Findings from Animal Disease Models
por: Zhang, Li, et al.
Publicado: (2022)

HIF-1α Overexpression Induces Angiogenesis in Mesenchymal Stem Cells
por: Razban, Vahid, et al.
Publicado: (2012)

Epithelial-Mesenchymal Transition in tumor microenvironment
por: Jing, Yingying, et al.
Publicado: (2011)

Synthesis and Cytotoxic Activity of Novel Tetrahydrocurcumin Derivatives Bearing Pyrazole Moiety
por: Mahal, Ahmed, et al.
Publicado: (2017)

Tetrahydrocurcumin (THC) enhanced the clearance of Cryptococcus deneoformans during infection in vivo
por: He, Tianli, et al.
Publicado: (2023)

Research models and mesenchymal/epithelial plasticity of osteosarcoma
por: Yu, Xiaobin, et al.
Publicado: (2021)

Exosomes from human umbilical cord mesenchymal stem cells enhance fracture healing through HIF‐1α‐mediated promotion of angiogenesis in a rat model of stabilized fracture
por: Zhang, Yuntong, et al.
Publicado: (2019)

HIF-2α-ILK Is Involved in Mesenchymal Stromal Cell Angiogenesis in Multiple Myeloma Under Hypoxic Conditions
por: Zhang, Xiaoying, et al.
Publicado: (2018)

Effects of Tetrahydrocurcumin on Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor Expression in Cervical Cancer Cell-Induced Angiogenesis in Nude Mice
por: Yoysungnoen, Bhornprom, et al.
Publicado: (2015)

Siglec-15-induced autophagy promotes invasion and metastasis of human osteosarcoma cells by activating the epithelial–mesenchymal transition and Beclin-1/ATG14 pathway
por: Zheng, Bingxin, et al.
Publicado: (2022)

Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids
por: Novaes, Júlia T., et al.
Publicado: (2017)

Curcumin Differs from Tetrahydrocurcumin for Molecular Targets, Signaling Pathways and Cellular Responses
por: Aggarwal, Bharat B., et al.
Publicado: (2014)

Polysaccharide Matrices for the Encapsulation of Tetrahydrocurcumin—Potential Application as Biopesticide against Fusarium graminearum
por: Loron, Anne, et al.
Publicado: (2021)

LINC00265 targets miR-382-5p to regulate SAT1, VAV3 and angiogenesis in osteosarcoma
por: Xiao, Ying, et al.
Publicado: (2020)

HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer
por: Zhang, Wenjing, et al.
Publicado: (2015)

HIF‐1α/VEGF signaling‐mediated epithelial–mesenchymal transition and angiogenesis is critically involved in anti‐metastasis effect of luteolin in melanoma cells
por: Li, Chunyu, et al.
Publicado: (2019)

Peiminine Induces G0/G1-Phase Arrest, Apoptosis, and Autophagy via the ROS/JNK Signaling Pathway in Human Osteosarcoma Cells in Vitro and in Vivo
por: Yu, Lei, et al.
Publicado: (2021)

NDUFA4L2 Regulated by HIF-1α Promotes Metastasis and Epithelial–Mesenchymal Transition of Osteosarcoma Cells Through Inhibiting ROS Production
por: Xu, Wen-Ning, et al.
Publicado: (2020)

MAGE‐C3 promotes cancer metastasis by inducing epithelial‐mesenchymal transition and immunosuppression in esophageal squamous cell carcinoma
por: Wu, Qingnan, et al.
Publicado: (2021)

Effects of Tetrahydrocurcumin on Tumor Growth and Cellular Signaling in Cervical Cancer Xenografts in Nude Mice
por: Yoysungnoen, Bhornprom, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9e91ovnfi2ba9plonnsk75ca9m