A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase β in colorectal cancer in vivo and in vitro

Here we report that a novel synthesized compound (E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP) which exhibits better stability, drug-likeness and anti-cancer effect than (E)-2,4-bis(p-hydroxyphenyl)-2-butenal (BHPB) that we previously reported. Of all newly synthesized BHPB analog...

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Detalles Bibliográficos
Autores principales: Zheng, Jie, Park, Mi Hee, Lee, Hee Pom, Hyun, Byung Kook, Chun, Hyung Ok, Jung, Sung Hee, Seo, Hyun Ok, Ham, Young Wan, Han, Sang-Bae, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710921/
https://www.ncbi.nlm.nih.gov/pubmed/29207641
http://dx.doi.org/10.18632/oncotarget.20440

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