Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC

Tumor-associated macrophages (TAMs) are strongly associated with poor survival in neuroblastomas that lack MYCN amplification. To study TAM action in neuroblastomas, we used a novel murine model of spontaneous neuroblastoma lacking MYCN amplification, and observed recruitment and polarization of TAM...

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Detalles Bibliográficos
Autores principales: Hadjidaniel, Michael D., Muthugounder, Sakunthala, Hung, Long T., Sheard, Michael A., Shirinbak, Soheila, Chan, Randall Y., Nakata, Rie, Borriello, Lucia, Malvar, Jemily, Kennedy, Rebekah J., Iwakura, Hiroshi, Akamizu, Takashi, Sposto, Richard, Shimada, Hiroyuki, DeClerck, Yves A., Asgharzadeh, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710942/
https://www.ncbi.nlm.nih.gov/pubmed/29207662
http://dx.doi.org/10.18632/oncotarget.21066

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