Cargando…

Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation

Thoracic endovascular repair (TEVAR) is an effective treatment for type B aortic dissection (TBAD). Here, we evaluated the early-midterm effectiveness and safety of TEVAR for treating TBAD patients after renal transplantation. Six patients with TBAD treated with TEVAR after renal transplantation wer...

Descripción completa

Detalles Bibliográficos
Autores principales: Shu, Chang, Xiong, QingGen, Qiu, Jian, Luo, MingYao, Fang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710952/
https://www.ncbi.nlm.nih.gov/pubmed/29207672
http://dx.doi.org/10.18632/oncotarget.21399
_version_ 1783282977424277504
author Shu, Chang
Xiong, QingGen
Qiu, Jian
Luo, MingYao
Fang, Kun
author_facet Shu, Chang
Xiong, QingGen
Qiu, Jian
Luo, MingYao
Fang, Kun
author_sort Shu, Chang
collection PubMed
description Thoracic endovascular repair (TEVAR) is an effective treatment for type B aortic dissection (TBAD). Here, we evaluated the early-midterm effectiveness and safety of TEVAR for treating TBAD patients after renal transplantation. Six patients with TBAD treated with TEVAR after renal transplantation were recruited between February 2012 and December 2016. They were then followed up with clinical examinations and computed tomography angiography (CTA). TEVAR was successfully performed in all patients (100%), and the primary tear sites were well covered by stents with or without coverage of the left subclavian artery. No severe complications occurred in any patient during perioperative period. The one-year survival rate was 100%, one patient died of renal graft failure and heart failure four years after TEVAR; the remaining five patients (83.3%) survived and exhibited no severe complications. Our findings show that TEVAR provides satisfactory short-midterm results for TBAD patients after renal transplantation. Moreover, our experience shows that it need relative longer proximal landing zone to prevent the endoleak and recurrence. However, regular hematodialysis, long-term immunosuppressive therapy, and blood pressure control remain crucial factors to prolong survival. Long-term follow-up studies are needed to evaluate the long-term prognosis in these patients.
format Online
Article
Text
id pubmed-5710952
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-57109522017-12-04 Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation Shu, Chang Xiong, QingGen Qiu, Jian Luo, MingYao Fang, Kun Oncotarget Research Paper Thoracic endovascular repair (TEVAR) is an effective treatment for type B aortic dissection (TBAD). Here, we evaluated the early-midterm effectiveness and safety of TEVAR for treating TBAD patients after renal transplantation. Six patients with TBAD treated with TEVAR after renal transplantation were recruited between February 2012 and December 2016. They were then followed up with clinical examinations and computed tomography angiography (CTA). TEVAR was successfully performed in all patients (100%), and the primary tear sites were well covered by stents with or without coverage of the left subclavian artery. No severe complications occurred in any patient during perioperative period. The one-year survival rate was 100%, one patient died of renal graft failure and heart failure four years after TEVAR; the remaining five patients (83.3%) survived and exhibited no severe complications. Our findings show that TEVAR provides satisfactory short-midterm results for TBAD patients after renal transplantation. Moreover, our experience shows that it need relative longer proximal landing zone to prevent the endoleak and recurrence. However, regular hematodialysis, long-term immunosuppressive therapy, and blood pressure control remain crucial factors to prolong survival. Long-term follow-up studies are needed to evaluate the long-term prognosis in these patients. Impact Journals LLC 2017-09-30 /pmc/articles/PMC5710952/ /pubmed/29207672 http://dx.doi.org/10.18632/oncotarget.21399 Text en Copyright: © 2017 Shu et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Shu, Chang
Xiong, QingGen
Qiu, Jian
Luo, MingYao
Fang, Kun
Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation
title Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation
title_full Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation
title_fullStr Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation
title_full_unstemmed Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation
title_short Thoracic endovascular aortic repair for type B aortic dissection after renal transplantation
title_sort thoracic endovascular aortic repair for type b aortic dissection after renal transplantation
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710952/
https://www.ncbi.nlm.nih.gov/pubmed/29207672
http://dx.doi.org/10.18632/oncotarget.21399
work_keys_str_mv AT shuchang thoracicendovascularaorticrepairfortypebaorticdissectionafterrenaltransplantation
AT xiongqinggen thoracicendovascularaorticrepairfortypebaorticdissectionafterrenaltransplantation
AT qiujian thoracicendovascularaorticrepairfortypebaorticdissectionafterrenaltransplantation
AT luomingyao thoracicendovascularaorticrepairfortypebaorticdissectionafterrenaltransplantation
AT fangkun thoracicendovascularaorticrepairfortypebaorticdissectionafterrenaltransplantation