Sevoflurane causes greater QTc interval prolongation in chronically hyperglycemic patients than in normoglycemic patients

QTc interval prolongation is a serious diabetic complication and increases mortality rate. Hyperglycemia inhibits the rapid component of delayed rectifier potassium channel currents (Ikr) and prolongs the QTc interval on electrocardiograms. Sevoflurane also inhibits the Ikr and causes QTc interval p...

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Detalles Bibliográficos
Autores principales: Kimura, Seishi, Nakao, Shinichi, Kitaura, Atsuhiro, Iwamoto, Tatushige, Houri, Kei, Matsushima, Mayuka, Hamasaki, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711029/
https://www.ncbi.nlm.nih.gov/pubmed/29194447
http://dx.doi.org/10.1371/journal.pone.0188555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711029/
https://www.ncbi.nlm.nih.gov/pubmed/29194447
http://dx.doi.org/10.1371/journal.pone.0188555

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