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A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix

Intracavitary brachytherapy (ICBT) and interstitial brachytherapy (IB) techniques are commonly practiced for treating carcinoma of the cervix, either alone or in combination with external beam radiotherapy. Both these brachytherapy techniques have their own advantages and limitations in terms of tum...

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Autores principales: Bansal, Anil K., Semwal, Manoj K., Sharma, Daya N., Thulkar, Sanjay, Julka, Pramod K., Rath, Goura K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711042/
https://www.ncbi.nlm.nih.gov/pubmed/24892331
http://dx.doi.org/10.1120/jacmp.v15i3.4509
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author Bansal, Anil K.
Semwal, Manoj K.
Sharma, Daya N.
Thulkar, Sanjay
Julka, Pramod K.
Rath, Goura K.
author_facet Bansal, Anil K.
Semwal, Manoj K.
Sharma, Daya N.
Thulkar, Sanjay
Julka, Pramod K.
Rath, Goura K.
author_sort Bansal, Anil K.
collection PubMed
description Intracavitary brachytherapy (ICBT) and interstitial brachytherapy (IB) techniques are commonly practiced for treating carcinoma of the cervix, either alone or in combination with external beam radiotherapy. Both these brachytherapy techniques have their own advantages and limitations in terms of tumor coverage and normal tissue sparing. Limited studies have been reported comparing the dosimetric features of these two techniques, especially from a single institution. We carried out a prospective clinical dosimetric comparison between ICBT and IB for patients treated at one center to bring out the inherent dosimetric features of these to two techniques. The study was carried out on 26 patients treated with ICBT and 55 with IB using CT‐based planning. Of the 55 patients treated with IB, 27 included tandem source loading (IBT) and 28 without the tandem loading (IBWT). The high‐dose volumes covered by 200% and 180% isodose surfaces were considerably larger in ICBT as compared to IB, whereas the treated volume was larger in IB as compared to ICBT. The bladder and rectal doses were the highest in ICBT and IBWT, respectively. The larger treated volume in IB as compared to ICBT was mainly because patients with larger tumor volumes were generally considered for IB. The results also indicated that in interstitial brachytherapy, better rectal sparing was achieved by including the tandem for treatment delivery. PACS numbers: 87.53.Bn, 87.53.Jw, 87.55.D‐, 87.55.dk
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spelling pubmed-57110422018-04-02 A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix Bansal, Anil K. Semwal, Manoj K. Sharma, Daya N. Thulkar, Sanjay Julka, Pramod K. Rath, Goura K. J Appl Clin Med Phys Radiation Oncology Physics Intracavitary brachytherapy (ICBT) and interstitial brachytherapy (IB) techniques are commonly practiced for treating carcinoma of the cervix, either alone or in combination with external beam radiotherapy. Both these brachytherapy techniques have their own advantages and limitations in terms of tumor coverage and normal tissue sparing. Limited studies have been reported comparing the dosimetric features of these two techniques, especially from a single institution. We carried out a prospective clinical dosimetric comparison between ICBT and IB for patients treated at one center to bring out the inherent dosimetric features of these to two techniques. The study was carried out on 26 patients treated with ICBT and 55 with IB using CT‐based planning. Of the 55 patients treated with IB, 27 included tandem source loading (IBT) and 28 without the tandem loading (IBWT). The high‐dose volumes covered by 200% and 180% isodose surfaces were considerably larger in ICBT as compared to IB, whereas the treated volume was larger in IB as compared to ICBT. The bladder and rectal doses were the highest in ICBT and IBWT, respectively. The larger treated volume in IB as compared to ICBT was mainly because patients with larger tumor volumes were generally considered for IB. The results also indicated that in interstitial brachytherapy, better rectal sparing was achieved by including the tandem for treatment delivery. PACS numbers: 87.53.Bn, 87.53.Jw, 87.55.D‐, 87.55.dk John Wiley and Sons Inc. 2014-05-08 /pmc/articles/PMC5711042/ /pubmed/24892331 http://dx.doi.org/10.1120/jacmp.v15i3.4509 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Bansal, Anil K.
Semwal, Manoj K.
Sharma, Daya N.
Thulkar, Sanjay
Julka, Pramod K.
Rath, Goura K.
A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix
title A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix
title_full A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix
title_fullStr A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix
title_full_unstemmed A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix
title_short A patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix
title_sort patient‐based dosimetric study of intracavitary and interstitial brachytherapy in advanced stage carcinoma of the cervix
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711042/
https://www.ncbi.nlm.nih.gov/pubmed/24892331
http://dx.doi.org/10.1120/jacmp.v15i3.4509
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