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A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances

The aim is to study beam characteristics at large distances when focusing on the electron component. In particular, to investigate the utility of spoilers with various thicknesses as an electron source, as well as the effect of different spoiler‐to‐surface distances (STSD) on the beam characteristic...

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Autores principales: Chakarova, Roumiana, Krantz, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711064/
https://www.ncbi.nlm.nih.gov/pubmed/24892344
http://dx.doi.org/10.1120/jacmp.v15i3.4708
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author Chakarova, Roumiana
Krantz, Marcus
author_facet Chakarova, Roumiana
Krantz, Marcus
author_sort Chakarova, Roumiana
collection PubMed
description The aim is to study beam characteristics at large distances when focusing on the electron component. In particular, to investigate the utility of spoilers with various thicknesses as an electron source, as well as the effect of different spoiler‐to‐surface distances (STSD) on the beam characteristics and, consequently, on the dose in the superficial region. A MC model of a 15 MV Varian accelerator, validated earlier by experimental data at isocenter and extended distances used in large‐field total body irradiation, is applied to evaluate beam characteristics at distances larger than 400 cm. Calculations are carried out using BEAMnrc/DOSXYZnrc code packages and phase space data are analyzed by the beam data processor BEAMdp. The electron component of the beam is analyzed at isocenter and extended distances, with and without spoilers as beam modifiers, assuming vacuum or air surrounding the accelerator head. Spoiler thickness of 1.6 cm is found to be optimal compared to thicknesses of 0.8 cm and 2.4 cm. The STSD variations should be taken into account when treating patients, in particular when the treatment protocols are based on a fixed distance to the patient central sagittal plane, and also, in order to maintain high dose in the superficial region. PACS numbers: 87.55.D‐, 87.55.de, 87.55.K‐
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spelling pubmed-57110642018-04-02 A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances Chakarova, Roumiana Krantz, Marcus J Appl Clin Med Phys Radiation Oncology Physics The aim is to study beam characteristics at large distances when focusing on the electron component. In particular, to investigate the utility of spoilers with various thicknesses as an electron source, as well as the effect of different spoiler‐to‐surface distances (STSD) on the beam characteristics and, consequently, on the dose in the superficial region. A MC model of a 15 MV Varian accelerator, validated earlier by experimental data at isocenter and extended distances used in large‐field total body irradiation, is applied to evaluate beam characteristics at distances larger than 400 cm. Calculations are carried out using BEAMnrc/DOSXYZnrc code packages and phase space data are analyzed by the beam data processor BEAMdp. The electron component of the beam is analyzed at isocenter and extended distances, with and without spoilers as beam modifiers, assuming vacuum or air surrounding the accelerator head. Spoiler thickness of 1.6 cm is found to be optimal compared to thicknesses of 0.8 cm and 2.4 cm. The STSD variations should be taken into account when treating patients, in particular when the treatment protocols are based on a fixed distance to the patient central sagittal plane, and also, in order to maintain high dose in the superficial region. PACS numbers: 87.55.D‐, 87.55.de, 87.55.K‐ John Wiley and Sons Inc. 2014-05-08 /pmc/articles/PMC5711064/ /pubmed/24892344 http://dx.doi.org/10.1120/jacmp.v15i3.4708 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Chakarova, Roumiana
Krantz, Marcus
A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
title A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
title_full A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
title_fullStr A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
title_full_unstemmed A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
title_short A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
title_sort monte carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711064/
https://www.ncbi.nlm.nih.gov/pubmed/24892344
http://dx.doi.org/10.1120/jacmp.v15i3.4708
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