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A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances
The aim is to study beam characteristics at large distances when focusing on the electron component. In particular, to investigate the utility of spoilers with various thicknesses as an electron source, as well as the effect of different spoiler‐to‐surface distances (STSD) on the beam characteristic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711064/ https://www.ncbi.nlm.nih.gov/pubmed/24892344 http://dx.doi.org/10.1120/jacmp.v15i3.4708 |
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author | Chakarova, Roumiana Krantz, Marcus |
author_facet | Chakarova, Roumiana Krantz, Marcus |
author_sort | Chakarova, Roumiana |
collection | PubMed |
description | The aim is to study beam characteristics at large distances when focusing on the electron component. In particular, to investigate the utility of spoilers with various thicknesses as an electron source, as well as the effect of different spoiler‐to‐surface distances (STSD) on the beam characteristics and, consequently, on the dose in the superficial region. A MC model of a 15 MV Varian accelerator, validated earlier by experimental data at isocenter and extended distances used in large‐field total body irradiation, is applied to evaluate beam characteristics at distances larger than 400 cm. Calculations are carried out using BEAMnrc/DOSXYZnrc code packages and phase space data are analyzed by the beam data processor BEAMdp. The electron component of the beam is analyzed at isocenter and extended distances, with and without spoilers as beam modifiers, assuming vacuum or air surrounding the accelerator head. Spoiler thickness of 1.6 cm is found to be optimal compared to thicknesses of 0.8 cm and 2.4 cm. The STSD variations should be taken into account when treating patients, in particular when the treatment protocols are based on a fixed distance to the patient central sagittal plane, and also, in order to maintain high dose in the superficial region. PACS numbers: 87.55.D‐, 87.55.de, 87.55.K‐ |
format | Online Article Text |
id | pubmed-5711064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57110642018-04-02 A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances Chakarova, Roumiana Krantz, Marcus J Appl Clin Med Phys Radiation Oncology Physics The aim is to study beam characteristics at large distances when focusing on the electron component. In particular, to investigate the utility of spoilers with various thicknesses as an electron source, as well as the effect of different spoiler‐to‐surface distances (STSD) on the beam characteristics and, consequently, on the dose in the superficial region. A MC model of a 15 MV Varian accelerator, validated earlier by experimental data at isocenter and extended distances used in large‐field total body irradiation, is applied to evaluate beam characteristics at distances larger than 400 cm. Calculations are carried out using BEAMnrc/DOSXYZnrc code packages and phase space data are analyzed by the beam data processor BEAMdp. The electron component of the beam is analyzed at isocenter and extended distances, with and without spoilers as beam modifiers, assuming vacuum or air surrounding the accelerator head. Spoiler thickness of 1.6 cm is found to be optimal compared to thicknesses of 0.8 cm and 2.4 cm. The STSD variations should be taken into account when treating patients, in particular when the treatment protocols are based on a fixed distance to the patient central sagittal plane, and also, in order to maintain high dose in the superficial region. PACS numbers: 87.55.D‐, 87.55.de, 87.55.K‐ John Wiley and Sons Inc. 2014-05-08 /pmc/articles/PMC5711064/ /pubmed/24892344 http://dx.doi.org/10.1120/jacmp.v15i3.4708 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Chakarova, Roumiana Krantz, Marcus A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances |
title | A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances |
title_full | A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances |
title_fullStr | A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances |
title_full_unstemmed | A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances |
title_short | A Monte Carlo evaluation of beam characteristics for total body irradiation at extended treatment distances |
title_sort | monte carlo evaluation of beam characteristics for total body irradiation at extended treatment distances |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711064/ https://www.ncbi.nlm.nih.gov/pubmed/24892344 http://dx.doi.org/10.1120/jacmp.v15i3.4708 |
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